In those analyses, combined Ki67-p53 status, tumor size and chemotherapy was a significant prognostic indicators of DFS (P < 0.0001, P = 0.0001 and P = 0.0028, respectively; Table 3) and combined Ki67-p53 status was an only significant prognostic indicator of OS (P = 0.0081, Table 4). The gene discussed is MKI67; the disease is neoplasm.