This is underscored by the omission in the METABRIC dataset of ZNF703, which resides in the amplification of the 8p12 locus that includes FGFR1. We have recently described ZNF703 as a driver [29] in luminal B cancers; however, DriverNet was not positioned to identify it due to its absence in the Reactome database. This evidence concerns the gene ZNF703 and cancer.