Additionally, serum concentration of MIC-1 and CA19-9, but not NGAL, were found to be higher in the PC patient group than in CP patients (1.6 ng/mL (p = 0.003), 31.8 U/mL (p<0.001), and 111.1 ng/mL (P>0.05) respectively) (Table 2). This evidence concerns the gene GDF15 and pachyonychia congenita.