WLS and myelodysplastic syndrome: Abnormal expression of the transcription factor ectopic viral integration site 1 (EVI) and its variant myelodysplastic syndrome 1 (MDS)/EVI, generated from the alternative splicing of the transcript of the MDS gene that linked the exon 2 of MDS to the exon 2 of EVI, have been implicated in a number of epithelial cancers and directly linked to severity of breast, leukemia, ovarian, and intestinal cancers [11]–[16].