Concordant with this donor group selection, analysis of donor juvenile male cd45- [cd34+/kdr+]EPCs by FACS revealed that juvenile male non-stroke prone rats exhibited significantly higher numbers of total cd45- [cd34+/kdr+]EPCs and DEspR- EPCs (Tukey’s all pairwise comparison P<0.0001 for both respectively) compared to 4 m stroke-prone spTg25+ female rats (Figure 3A). This evidence concerns the gene FBXW7-AS1 and Stroke.