However, distinguishing the cd45- EPC-subset as the per cent fraction of cd45- [cd34+/kdr+]EPCs in total [cd34+/kdr+]EPCs revealed significant decrease in 17 wk-old males and females, ANOVA P<0.0001, (Figure 1B) thus indicating informativeness of the cd45- [cd34+/kdr+]EPC subset in this rat stroke model. This evidence concerns the gene CD34 and stroke disorder.