Additionally, since the queried pathway-specific molecular profile of juvenile stroke-prone spTg25+ rat cd45- [cd34+/kdr+]EPCs is similar to the molecular profile of old non-stroke prone rat cd45- [cd34+/kdr+]EPCs, it becomes apparent that stroke susceptibility induced by developmental programming via early-life Na-exposure [7] accelerates age-associated gene expression changes in spTg25+ rat cd45- [cd34+/kdr+]EPCs in both despr+ despr- subtypes. Here, FBXW7-AS1 is linked to Stroke.