NFKB1 and infection: In summary, our screening of the LOPAC library in the phagocytosis and NF-κB assays identified two kinase inhibitors, rac-2-Ethoxy-3-octadecanamido-1-propylphosphocholine and wortmannin, which strongly inhibit Y. pestis internalization and pathogen-induced NF-κB activation during the early stages of infection.