As shown in Figure 6A, we observed that upon MVMp or H-1PV infection both transcription factors STAT1 and STAT2 become activated (phosphorylated) and their expression, as well as that of another ISG the cytosolic protein kinase PKR, increased...Moreover, RT-PCR analysis of the transcription of α and β IFNs in the latter samples revealed also an up-regulation compared to mock-treated cells (Figure 6B). The gene discussed is EIF2AK2; the disease is infection.