Similar to our results in glioma, it was previously reported that miR-195 inhibited the hepatocellular carcinoma cells and hepatic stellate cells proliferation, respectively through targeting CyclinD1and CyclinE1 [51]–[52], indicating that the miR-195-downregulation-induced Cyclin D1/Cyclin E1 expression might be Universal among different types of tumors. The gene discussed is CCND1; the disease is central nervous system cancer.