MKI67 and neoplasm: After universal correlation analysis, significant differences were observed in age, histological grade, metastatic nodes, postoperative distant metastasis, and molecular subtypes between Ki67+ and Ki67− cases (P = 0.01, 0.001, 0.001, 0.001 and 0.001, respectively), while these differences were not observed in tumor size (P = 0.118) (Table 1).