Also, LB are present in other synucleinopathies as well as other neurodegenerative diseases, where, in general, α-synuclein is not known to be a primary causative factor, and a proportion of clinically normal people have LB, although this may be sub-threshold pathology [6]–[8], [68]–[70]. The gene discussed is SNCA; the disease is neurodegenerative disease.