NPPB and chronic kidney disease: In all patients, GFR was estimated using the modified MDRD equation for Chinese patients with CKD [19] and was correlated with age(p<0.0001), gender(p = 0.007), 24-h mean heart rate(p = 0.001), LVMI(p<0.0001), LAVI(p<0.0001), deceleration time(p = 0.003), IVRT(p<0.0001), E/E′ (p<0.0001), lgNT-proBNP(p<0.0001) and lgUACR(p<0.0001) in Pearson’s correlation analysis (Table 3).