SIRT1 and coronary artery disorder: Sirt1 mRNA levels in monocytes were significantly higher in healthy controls (0.0791±0.019; n = 13; Figure 1C) as compared to CAD (0.041±0.004; n = 19; P<0.05 vs control) and ACS patients (0.042±0.005; n = 18; P<0.05 vs control).