TMEM245 and schizophrenia: Especially we detected five SNPs in the first two genes/loci strongly associated with negative symptoms of schizophrenia (Pmeta-analysis<6.22×10−6), which included three SNPs in the BCL9 gene: rs583583 showed the strongest association at a Pmeta-analysis of 6.00×10−7 and two SNPs in the C9orf5 (the top SNP is rs643410 with a p = 1.29 ×10−6).