For the type 2 diabetes-associated SNPs, the PheWAS-identified associations were observed for the phenotype-classes of “Dieting” (IGFBP2 rs4402960) in European Americans, “Artery” and “Ever Smoked” (ADAMTS9 rs4607103) in European Americans, “Hypertension” (NOTCH2 rs10923931) in African Americans, “Heart Rate” (LGR5 rs7961581) in European Americans, and “Menstruation” (specifically age at menarche) in European Americans (FTO rs8050136). Here, IGFBP2 is linked to type 2 diabetes mellitus.