In humans, the hTRM9L gene maps to the end of human chromosome 8, a region commonly lost or silenced in many different cancers, including colorectal carcinoma (Ilyas et al, 1999; Kerangueven et al, 1995; Knowles et al, 1993; Prasad et al, 1998). This evidence concerns the gene TRMT9B and colorectal carcinoma.