About the mechanisms why SATB1 influence the proliferation and invasion for small lung cancer cell, so far there is no much research on that, however, lots of study about the roles of SATB1 in breast cancer and other cancers have been investigated, Han et al. use gene chip to find SATB1 can induce the change of more than 1000 genes’ expression[3]. The gene discussed is SATB1; the disease is cancer.