Takayama et al. [37] reported that TGF-β1 caused EMT of SCCVII cells, and they found EMT-like changes through resected human mandibles with gingival SCC, in which immunohistochemical staining of E-cad was weak in tumour mass-margin comparing with the tumour mass-centre. The gene discussed is TGFB1; the disease is gingivitis.