In addition, accumulating evidence indicates that the Glasgow Prognostic Score (GPS) system based on inflammation criteria and including only serum C-reactive protein (CRP) and albumin, is a reliant and practical scoring system for outcome prognostication in patients with advanced cancer, such as colorectal cancer [6,7], esophageal cancer [8], gastric cancer [9], pancreatic cancer [10], and lung cancer [11]. This evidence concerns the gene CRP and esophageal cancer.