Due to the correlation between CRP, albumin and GPS and between GPS and mGPS, variables (AST, total serum bilirubin, Plt, AFP, GPS, CLIP score, JIS score, BCLC score, TNM stage, maximal tumor diameter, multiple nodules, vascular invasion and extrahepatic metastasis) were tested in multivariate analysis. This evidence concerns the gene CRP and neoplasm.