After infection, mRNA transcript levels of CCL3, CCL5, CCL7 and CCL19 were significantly and consistently increased in the brains of MyD88+/+ mice compared to the brains of MyD88−/− mice (about 2,500 fold for CCL3; 1,500 fold for CCL5; 70 fold for CCL7; and 20 fold for CCL19, compared to non-infected) (Figure 5D). This evidence concerns the gene MYD88 and infection.