TAT and Kaposi's sarcoma: The pathogenesis process of KS appears to be complex, involving various mechanisms dependent on both viral and cellular activities, and is related to inflammation and angiogenesis promoted by endothelial growth factors (β-FGF, PDGF, VEGF) and HIV-Tat as well as cell proliferation and anti-apoptotic activity through vBCL2 [49,66,67].