The active Bac-ELP1-H1 polypeptide, or control polypeptides lacking the H1 peptide (Bac-ELP1) or utilizing the non-thermally responsive version of ELP (Bac-ELP2-H1) were injected IV, and, in hyperthermia groups, hyperthermia was applied to the tumor site using the thermal cycling protocol immediately after each injection. The gene discussed is NR5A1; the disease is neoplasm.