Taken together with data showing the response of myeloid cells to PK2, it is clear that PKRA7 acts to suppress pancreatic cancer by blocking the ability of PK2 to induce myeloid cells mobilization from the bone marrow specifically as well as PK2’s direct effect on the tumor microenvironment through pro-migratory responses. The gene discussed is PROK2; the disease is pancreatic neoplasm.