RUNX1T1 and acute myeloid leukemia: For example, in the chimeric AML1/ETO protein produced by the 8;21 translocation associated with 12–15% of acute myeloid leukemias, the ETO MYND domain binds the SMRT and NCoR corepressors [11]–[13], and MYND domain of the adenoviral protein BS69 was shown to interact with NCoR [14].