Since miRNAs modulate the expression of their target genes and FoxM1 is a predicted target of miR-200, we asked the question whether ectopic expression of miR-200 can affect the expression of FoxM1. Such an observation will suggest that DIM/Herceptin-mediated regulation of miR-200 is important for the eventual regulation of FoxM1, which ultimately defines the aggressiveness, and possibly, the drug resistance of breast cancer cells. The gene discussed is FOXM1; the disease is breast carcinoma.