Tumor genesis can be caused by genetic alterations in Axin, Adenomatous Polyposis Coli (APC), β-catenin; loss of DKK, SFRP & WIF; and mutations in β-catenin-Axin-adenomatous polyposis coli (APC)-glycogen synthase kinase (GSK)-3β multi-protein complex [9]. This evidence concerns the gene APC and neoplasm.