TNF and bacterial infectious disease: The lack of an association of circulating miR-150 with the presence of sepsis was further substantiated by correlation analyses revealing that serum miR-150 levels were not significantly correlated to established markers of systemic inflammation and bacterial infection such as C-reactive protein (CRP), procalcitonin (PCT), interleukin-6 (IL-6), interleukin-10 (IL-10) or tumor necrosis factor (TNF) in critically ill patients (Table 3).