Nevertheless, upregulation of SOCS3 has been reported in CTCL and other malignancies in association with elevated JAK-STAT signalling [35], and in JAK2V617F positive myeloproliferative disorders together with STAT3 and STAT5B [36], consistent with our findings. This evidence concerns the gene SOAT1 and primary cutaneous T-cell non-Hodgkin lymphoma.