AKT1 and neoplasm: Other AKT inhibitors such as isoselenocyanates, API-2, SR13668, BI-69A11, GSK690693, and MK-2206 have been shown to have anti-tumor activity in suppressing tumor growth and are undergoing further testing (Forino et al., 2005; Karst et al., 2006; Rhodes et al., 2008; Sharma et al., 2009; Hirai et al., 2010).