KLK7 and Hyperglycemia: We can therefore conclude that, under physiologic conditions, the relevance of the vaspin–hK7 interaction may be limited, but the vaspin–hK7 ratio may change acutely after food ingestion before glucose-induced insulin levels peak or, on the other hand, under chronic conditions of hyperglycemia or other metabolic alterations under which the vaspin–hK7 interaction may become significantly relevant.