DNAJA4 encodes the heat shock protein, SLC7A11 an anion amino acid transporter, AKR1B10 and AKR1C1 are subunits for a reductase associated with cancer, ASPM and KIF20A are involved in mitotic spindle functions, ZFAND2A is a zinc-finger protein that is inducible by arsenite, and INHBA is known to inhibit cell proliferation and to have tumor-suppressor activity. The gene discussed is AKR1C1; the disease is cancer.