BCL2 and Stroke: Indeed, approaches for gene silencing that use short regulatory ncRNAs, including miRNAs and related short interfering RNAs (RNA interference) have already been used to identify new molecular targets for treating stroke, such as Bcl-2 and 19-kDa interacting protein 3 [97] and carboxyterminalmodulator protein [98]; however, RNA interference-based gene silencing for treating stroke has yet to advance beyond preliminary studies.