MTOR and posterior cortical atrophy: It should be noted that while the AKT and mammalian target of rapamycin (AKT/mTOR), AR, and Wnt/β-Catenin signaling pathways have been shown to be activated at the biochemical level (i.e., phosphorylation/activation of signaling proteins, nuclear translocation of signal proteins) in PCa specimens and cell lines, these earlier studies were not focused on PCa disparities and hence did not take into account the race/ethnicity of the patients from which the tissues were derived [63–65].