All 6 tested genes (STAT1, RHOA, ITGB5, MAPKAPK2, CNSK2A1, and PIK3CB), exhibiting higher expression in AA PCa specimens and AA PCa cell lines compared to the corresponding CA counterpart tissues/cell line, also displayed higher AR binding to their gene promoters in the AA PCa cell line E006AA compared to the CA PCa cell line VCaP (representing 100% success rate for validation). This evidence concerns the gene ITGB5 and posterior cortical atrophy.