UCP3 and type 2 diabetes mellitus: The T allele of the UCP3 -55C/T polymorphism has been associated with increased incidence of T2DM [59], higher BMI [60], [61], lower BMI [62], [63], higher HDL cholesterol levels [62], larger waist circumference [64], and high total cholesterol and LDL cholesterol levels and reduced risk of T2DM [31].