IGF1R and laryngeal carcinoma: These results are in line with recently published important evidence on gene arrays [22] that highlight the importance of the IGFR-mediated molecular pathway in laryngeal carcinogenesis and progression; Of note, current treatment modalities in early stages of laryngeal cancer include surgical resection with or without adjuvant radiotherapy, as used in our cohort, rendering thus our results timely and clinically relevant.