Interestingly, the proliferation cluster of gene sets shows little association with survival in ER−/HER2− and HER2+ breast cancer and ovarian cancer and its subtypes, and it is the EMT, hypoxia, angiogenesis, and development-associated cluster of gene sets that are associated with poor prognosis in these diseases/subtypes with these pathways showing little association with poor prognosis in ER+ breast cancer. The gene discussed is ERBB2; the disease is ovarian carcinoma.