EZH2 and diffuse large B-cell lymphoma: Sixteen samples (13.2%) from 11 cases presented with the Y646 mutation for EZH2. Diagnoses included 9 FL, 2 DLBCL, 2 LBCL, 1 U-DLBCL/BL, 1 composite DLBCL/FL, and 1 small B-cell NHL.