In the univariate and multivariate logistic regression model, gender, age, weight, HBV or HCV coinfection, baseline dosing regimen, ALT or AST level, CD4 cell counts and viral load appeared to have no significant association with nevirapine trough concentration <3.0 μg/mL and <3.9 μg/mL at week 2, respectively (Table 3). The gene discussed is GPT; the disease is coinfection.