CASP1 and infection: Furthermore, infection with V. parahaemolyticus induced caspase-1 activation (production of p10 fragment by processing procaspase-1 (45 kDa)) and the processing (production of 17 kDa mature form)/release of proIL-1β (Figure 1B and 1C) as well as the release of LDH, a marker of lytic cell death (Figure 1D).