FLT1 and colorectal carcinoma: A study undertaken by Lambrechts et al. [64] identified a locus in VEGFR1, which correlates with increased VEGFR1 expression and poor outcome of bevacizumab-treated patients with metastatic pancreatic adenocarcinoma and metastatic renal-cell carcinoma, although no work has as yet been undertaken in the CRC setting.