Huh7 hepatocellular carcinoma cells resemble normal hepatocytes in that they express significant amounts of the liver-specific miR122 [27], and have previously been used as an in vitro model for adenovirus infection of liver cells to demonstrate the capacity of miR122 target sites to down-regulate E1A expression [22], [23]. The gene discussed is DHTKD1; the disease is adenoviridae infectious disease.