During the preparation of this manuscript, Germann et al. published a manuscript which demonstrated p68 (Ddx5) and the highly homologous p72 (Ddx17) protein have a dual role in the control of transcription of the pro-migratory NFAT5 transcription factor (in addition to their role in facilitating the inclusion of NFAT5 exon 5), in breast cancer cells [37]. The gene discussed is DDX17; the disease is breast cancer.