Other genes have been associated with T2DM such as TCF7L2, SLC30A8, HHEX, CDKAL1, IGF2BP2, CDKN2A/B, PPARG, KCNJ11, KCNQ1 and MTNR1B, as determined through genome-wide association studies (GWAS) [48], [49]. This evidence concerns the gene TCF7L2 and type 2 diabetes mellitus.