HLA-DRB1 and rheumatoid arthritis: In our report, the 6p21.32 region was implicated by three SNPS; rs4530903 upstream from HLA-DRB1 and HLA-DQA1, rs2621416 upstream of HLA-DQB2, and rs9268853 downstream of HLA-DRA, HLA-DRB5 and HLA-DRB1, but upstream of BTLN2. rs2621416 and rs9268853 have also been associated with risk for ulcerative colitis [18] and rheumatoid arthritis [19] respectively, both of which increases risk for certain types of lymphoma.