Crotoxin, a noncovalent complex (formed by two nonidentical subunits: a basic PLA2 crotoxinB and a nonenzymatic acidic crotoxinA) isolated from the venom of Crotalus durissus terrificus, exhibits a preferential cytotoxic activity against various types of tumor cells including K-562 cells [58], MCF-7 cells [59] and lung adenocarcinoma A549 cells. The gene discussed is PLA2G2A; the disease is lung adenocarcinoma.