When we infected Jurkat cells with wild-type (WT), Nef-deleted (ΔNef) or Vpu-deleted (ΔVpu) viruses, we found a significant difference between the WT and ΔVpu-infected cells, but not the WT and ΔNef infected cells on days 2 (Figure 4A) and 10 (Figure 4B) post-infection. The gene discussed is SGTA; the disease is infection.