GFAP and tuberous sclerosis: In FCD IIb and TSC specimens, albumin immunoreactivity, with diffuse cytoplasmatic staining, was detected in perilesional astrocytes and in perivascularly located balloon/giant cells in FCD IIb and TSC specimens (Figure4H,I,J,K); double labeling confirmed co-localization in GFAP positive cells (Figure4J,K).