Meanwhile, the MUC2 mRNA was decreased in tumor tissues with age > = 40 years than those with age < 40 years in HCC patients (Mean -ΔCt ± SE, -5.57 ± 1.89 and −1.29 ± 0.80, respectively) (p < 0.001). The gene discussed is MUC2; the disease is neoplasm.