BDNF and obesity due to melanocortin 4 receptor deficiency: Obesity risk was nominally associated with variation at the FAIM2 locus (OR = 1.58, 95% CI: 1.05–2.40, p = 0.025), and with a variant at the BDNF locus (OR = 1.72, 95% CI: 1.00–2.95, p = 0.028) (Table S2).