A study by Kovar et al. [16] suggests that Ewing's sarcoma is characterized by EWS fusions with FLI1 in 90–95% of cases, ERG in 5–10% of cases, and that FEV, ETV1, and ETV4 fusions occur in less than 1% of cases. The gene discussed is FLI1; the disease is Ewing sarcoma.