These chimericparticles have been used as a carrier protein of the influenza virus M2e protein.The fusion protein M2e-HBc has been produced in E. coli cells.Immunization with recombinant М2е-НВc proteasomes hasprotected mice against a lethal influenza infection even in the presence ofpreexisting antibodies against the HBc antigen [37]. Here, KRT88P is linked to influenza.